Immune checkpoint inhibitors (ICIs) are essential for urothelial carcinoma (UC) treatment.Fibroblast growth factor receptor (FGFR) alterations, as common oncogenic drivers in UC, have been Sound Bar Mount reported to drive T cell depletion of UC immune microenvironment via up-regulating FGFR signaling, which indicated FGFR alterations potentially r
In-silico model development and validation of the L5-S1 spinal unit
AbstractThe L5-S1 segment of the spine is highly susceptible to injury, frequently causing low back pain.The segment has gained a lot of scientific interest, leading to many experimental works that can be found describing its biomechanical characteristics.But, there is a lack of work focusing on its computational studies, which can significantly ai
Tidal wave phenomenon as a lever of tourist development in Greece- Halkis case
Tourist season in Halkis is nowadays limited to the three summer Fingerless Gloves months offering a resort for weekend tourists (Athens-Halkis).Halkis is given the opportunity to improvise and illustrate its cultural and historical elements that constitute her uniqueness by establishing a local development programme that would include alternate to